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One or more keywords matched the following items that are connected to Kirken, Robert
Item TypeName
Academic Article Uncoupling JAK3 activation induces apoptosis in human lymphoid cancer cells via regulating critical survival pathways.
Academic Article JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.
Academic Article Analysis of Janus tyrosine kinase phosphorylation and activation.
Academic Article Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex.
Academic Article Activation of receptor-associated tyrosine kinase JAK2 by prolactin.
Academic Article Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-gamma and interleukin-4 receptor-alpha.
Academic Article Two discrete regions of interleukin-2 (IL2) receptor beta independently mediate IL2 activation of a PD98059/rapamycin/wortmannin-insensitive Stat5a/b serine kinase.
Academic Article Concomitant inhibition of Janus kinase 3 and calcineurin-dependent signaling pathways synergistically prolongs the survival of rat heart allografts.
Academic Article Tyrphostin AG490 selectively inhibits activation of the JAK3/STAT5/MAPK pathway and rejection of rat heart allografts.
Academic Article Molecular actions of sirolimus: sirolimus and mTor.
Academic Article Specific inhibition of Stat5a/b promotes apoptosis of IL-2-responsive primary and tumor-derived lymphoid cells.
Academic Article Involvement of JAK-family tyrosine kinases in hematopoietin receptor signal transduction.
Academic Article JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization.
Academic Article Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.
Academic Article Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.
Academic Article Nitric oxide and thiol redox regulation of Janus kinase activity.
Concept Enzyme Activation
Academic Article Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways.
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  • Enzyme Activation
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